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Potential foot-and-mouth-disease vaccine components trialled in pigs

New research demonstrates that certain B-cell proteins provide pigs with long-lasting immunity to food-and-mouth disease.

2 February 2020, at 8:00am

According to a recently published abstract in Transboundary and Emerging Diseases, researchers have been able to isolate the synthetic protein B2T(mal) and demonstrate its ability to elicit B- and T-cell specific immune responses in pigs. In trials, two doses of B2T(mal) elicited an immune response that gave pigs reliable protection against type O foot-and-mouth disease virus (FMDV) challenges. After injection, the pigs retained immunity to FMDV challenges for up to 136 days (19-20 weeks).

Read the original abstract in Transboundary and Emerging Diseases.