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Classical Swine Fever In Hungary

by 5m Editor
24 January 2007, at 11:44am

HUNGARY - This is a report via the OIE on the outbreak of Classical Swine Fever in Hungary.

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Information received on 24/01/2007 from Mr Tibor Bálint, Chief Veterinary Officer, Animal Health and Food Control Department, Ministry of Agriculture and Rural Development , Budapest, Hungary

Summary

Report type Immediate notification
Start date 10/01/2007
Date of confirmation of event 22/01/2007
Report date 24/01/2007
Date submitted to OIE 25/01/2007
Reason for notification Reoccurrence of listed disease
Date of previous occurrence 05/1993
Manifestation of disease Clinical disease
Causal agent Classical swine fever virus
Nature of diagnosis Suspicion, Clinical, Laboratory (basic), Laboratory (advanced)
Report pertains to Entire country

New Outbreaks

Outbreak 1 Csesztve, Balassagyarmat, NOGRAD
Date of start of outbreak 10/01/2007
Outbreak status Continuing (or date resolved not submitted)
Epidemiological unit Not applicable
Affected animals
Species Susceptible Cases Deaths Destroyed Slaughtered
Wild species 1071 1 0 1 0
Affected population wild boar
Outbreak 2 Ipolytarnóc, Salgótarján, NOGRAD
Date of start of outbreak 12/01/2007
Outbreak status Continuing (or date resolved not submitted)
Epidemiological unit Not applicable
Affected animals
Species Susceptible Cases Deaths Destroyed Slaughtered
Wild species 1071 1 0 1 0
Affected population wild boar
Outbreak 3 Litke, Salgótarján, NOGRAD
Date of start of outbreak 10/01/2007
Outbreak status Continuing (or date resolved not submitted)
Epidemiological unit Not applicable
Affected animals
Species Susceptible Cases Deaths Destroyed Slaughtered
Wild species 1071 1 0 1 0
Affected population wild boar
Summary of outbreaks Total outbreaks: 3
Total animals affected
Species Susceptible Cases Deaths Destroyed Slaughtered
Wild species 3213 3 0 3 0
Outbreak statistics
Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible removed*
Wild species 0.09% 0.00% 0.00% 0.09%
* Removed from the susceptible population either through death, destruction or slaughter

Epidemiology

Source of infection
  • Contact with wild Species
Epidemiological comments The first, a clinically healthy wild boar, was shot near Csesztve on 10 January 2007. This animal was found to be positive on serological and virological (PCR) investigation. The second, a clinically healthy wild boar, was shot near Litke on 10 January 2007. The blood sample from this animal was unfit for serological investigation, but the sample from the tonsils was virologically (PCR) positive. The third was a wild boar shot near Ipolytarnóc on 12 January 2007 because of abnormal behaviour with neurological signs. The whole carcass was sent to the Veterinary Diagnostic Directorate in Budapest (the former Central Veterinary Institute), where the virological investigations (antigen capture ELISA and PCR) were positive.

The positive samples and, for comparative reasons, a vaccine C strain were amplified by PCR based on the protocol described by Elvander et al. in 1998 (Acta vet. Scand. Vol. 39, pages 251-264). The amplified products (partial 5’UTR fragment, 188 base pairs) were purified from agarose gels and sequenced with the primers used in PCR. Based on alignments and BLAST homology search results, we were able to determine that:
- The field sample sequences are identical but differ in 11 nucleotide positions compared with the vaccine strain in the examined region (the vaccine strain was 100% identical to the vaccine strain available in the GenBank).
- The greatest homology was found with the Swiss isolate “Switzerland 4/93“ (3 nucleotide difference) accession number: AF045072 described as similar to the Alfort/187 strain.
The results are preliminary, in order to elucidate the importance of the mutations or sequence differences, and we will perform two other PCR tests targeting the 3’ UTR and E2 regions.


Control measures

Measures already applied
  • Screening
  • Control of wildlife reservoirs
  • Zoning
  • Vaccination prohibited
  • No treatment of affected animals
Measures to be applied
  • None specified

Diagnostic test results

Laboratory name and type Veterinary Diagnostic Directorate of the Central Agricultural Office, Budapest (former Central Veterinary Institute) (National laboratory)
Tests and results
Species Test Test date Result
Wild species antigen (Ag) detection ELISA 22/01/2007 Positive
Wild species polymerase chain reaction (PCR) 22/01/2007 Positive

Map of outbreak locations

Location of current outbreaks

Click on map to zoom in.

5m Editor