Vaccine trial data versus lineage: What’s the best way to predict PRRS vaccine performance?

An interview with Eva Jablonski, DVM PRRS Specialist Senior Technical Services Veterinarian at Zoetis.
calendar icon 29 June 2020
clock icon 2 minute read
References
References
1 Broad Institute. What is an ORF? Blog/11.30.10.
2 Opriessnig T, et al.
Genomic homology of ORF 5 gene sequence between modified live vaccine virus and porcine reproductive and respiratory syndrome virus challenge isolates is not predictive of vaccine efficacy.. J Swine Health Prod 13(5);246-253.
3 Ibid.
4 Shi M, et al.
Phylogeny-based evolutionary, demographical and geographical dissection of North American Type 2 porcine reproductive and respiratory syndrome viruses.
5 Paploski I, et al.
(2019) Temporal dynamics of co-circulating lineages of porcine reproductive and respiratory syndrome virus.. Front. Microbiol. Nov 1.
6 Ibid.
7 Ibid.
8 Opriessnig T, et al.
Genomic homology of ORF 5 gene sequence.
9 Prieto C, et al.
(2008) Similarity of European porcine reproductive and respiratory syndrome virus strains to vaccine strain is not necessarily predictive of the degree of protective immunity conferred.. Vet J. 2008:175;356-363.
10 Ibid.
11 Zoetis, LLC.
Data on file.. Study No. 19PRGBIO-01-04.
12 Aljets K, et al.
(2017) Field evaluation of vaccination of piglets at processing using Fostera PRRS.. Am Assoc Swine Vet annual meeting.
13 Angulo J, et al.
(2015) Efficacy of a PRRSV MLV vaccine against a genetically diverse range of PRRSV isolates.. Allen D. Leman Swine Conference.

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