Intradermal vaccination of sows: another step forwards in the control of PRRS

Needle-free vaccination by intradermal injection has many advantages and will go far in the efforts to eliminate PRRS.
calendar icon 31 October 2019
clock icon 7 minute read
Figure 1.
Figure 1.

The dermis represents an excellent site for vaccine delivery, being rich in resident dendritic cells (DC), lymph vessels and blood capillaries.

Figure 2.
Figure 2.

Hipradermic® needle-free jet injector for intradermal application of vaccines.

Figure 3.
Figure 3.

Comparison of intramuscular and intradermal administration in cell-mediated immunity against different field strains in UNISTRAIN® PRRS vaccinated gilts.

Figure 4.
Figure 4.

Comparison of duration of nasal shedding (left) and vertical transmission (right) after heterologous challenge in UNISTRAIN® PRRS intradermally vaccinated and non-vaccinated gilts.

Figure 5.
Figure 5.

Comparison of number (left) and weight (right) of weaned piglets born from UNISTRAIN® PRRS intradermally vaccinated and non-vaccinated gilts.

Different superscript letters indicate statistically significant differences (p<0.05) among groups.

References
References
1. Miranda, J. et al.
(2015) Vaccination with UNISTRAIN® PRRS in piglets reduces viremia and excretion of PRRSV after a heterologous challenge with a Spanish strain. International PRRS Congress, Ghent, Belgium.
2. Linhares DC. et al.
(2014) Comparison of time to PRRSv-stability and production losses between two exposure programs to control PRRSv in sow herds.. Prev Vet Med. 1;116(1-2):111-9
3. Busquet, M. et al.
(2015) Efficacy of UNISTRAIN® PRRS administered intradermally in piglets in a multicentric field trial. International PRRS International PRRS Congress, Ghent, Belgium.
4. E Kis, et al.
(2011) Devices for intradermal vaccination.. Vaccine 30. 523-38.
5. Chase, C. et al.
(2008) Needle-free injection technology in swine: Progress toward vaccine efficacy and pork quality.. Journal of Swine Health and Production. 16
6. Martinez Miró, S et al.
(2016) Causes, consequences and biomarkers of stress in swine: An update.. BMC Veterinary Research. 12. 10.1186
7. Martelli, P et al.
(2007) Protection and immune response in pigs intradermally vaccinated against porcine reproductive and respiratory syndrome (PRRS) and subsequently exposed to a heterologous European (Italian cluster) field strain.. Vaccine 30; 25 (17):3400-8
8. Busquet, M et al.
(2016) Intradermal vaccination with UNISTRAIN® PRRS in a mass vaccination in sows. IPVS & ESPHM Congress.
9. Miranda, J et al.
(2015) Heterologous cell-mediated immune responses against PRRS virus in gilts vaccinated intramuscularly and intradermally with UNISTRAIN® PRRS. ISERPD Congress 2015.
10. Simón-Grifé, M.
(2018) Intradermal vaccination with UNISTRAIN® PRRS in gilts reduces viraemia and vertical/horizontal transmission after a heterologous challenge. ESPHM Congress.
11. Simón-Grifé, M.
(2018) Intradermal vaccination with UNISTRAIN® PRRS in gilts improves the performance of their offspring. ESPHM Congress.

Lidia de Lucas

Hipra

Joel Miranda

HIPRA, Amer (Girona), Spain
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