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Phylogenetic Analysis of Porcine Parvoviruses from Swine Samples in China

by 5m Editor
13 September 2011, at 12:00am

This is the first report on the isolation of a Group III porcine parvovirus in China.

Porcine parvovirus (PPV) usually causes reproductive failure in sows, explain Xiaofang Hao and colleagues at the Chinese Academy of Agriculture Sciences in Lanzhou, PR China. The objective of their study, published recently in Virology Journal, was to analyse the phylogenetic distribution and perform molecular characterisation of PPVs isolated in China, as well as to identify two field strains, LZ and JY. The data used in this study contained the available sequences for NS1 and VP2 from GenBank, as well as the two Chinese strains.

Phylogenetic analysis showed that the PPV sequences are divided into four groups. The early Chinese PPV isolates are Group I viruses, and nearly all of the later Chinese PPV isolates are Group II viruses. LZ belongs to group II, whereas the JY strain is a Group III virus. This is the first report on the isolation of a Group III virus in China.

The detection of selective pressures on the PPV genome shows that the NS1 and VP2 genes are under purifying selection and positive selection, respectively. Moreover, the amino acids in the VP2 capsid are highly variable because of the positive selection.

The Lanzhou researchers conclude that their study provides new molecular data on PPV strains in China, and emphasises the importance of aetiological studies of PPV in pigs.

Reference

Hao X., Z. Lu, P. Sun, Y. Fu, Y. Cao, P. Li, X. Bai, H. Bao, B. Xie, Y. Chen, D. Li and Z. Liu. 2011. Phylogenetic analysis of porcine parvoviruses from swine samples in China. Virology Journal, 8:320 doi:10.1186/1743-422X-8-320

Further Reading

- You can view the full report by clicking here.


Further Reading

- Find out more information on porcine parvovirus (PPV) by clicking here.


September 2011