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Ileitis Treatments Comparison: Oral Vaccination V's antibiotics

by 5m Editor
11 December 2006, at 12:00am

By M. Y. C. Thaker and G. Bilkei - Comparison of the effects of oral vaccination and different antibiotic prophylactic treatments against Lawsonia intracellularis associated losses in a finishing pig unit with high prevalence of porcine proliferative enteropathy (PPE).

The aim of the present study was to compare the effects of oral vaccination and feed medication against Lawsonia intracellularis (LI) on the performance of growing-finishing pigs in a large Hungarian production unit with a high prevalence of LI infection. Pigs testing positive for LI infection were randomly divided into 4 groups and treated as follows:

  • Group one: growing pigs (n = 3810) were vaccinated against LI infection after entry into the growing-finishing unit with an avirulent live oral vaccine (Enterisol® Ileitis Boehringer Ingelheim Vetmedica, Inc., St. Joseph, USA).

  • Group two: growing pigs (n = 3799) received feed medicated with doxycycline (200 pp. doxycycline hyclate, Primadox® 50, ufamed AG, CH-6210 Sursee, Switzerland) over a 3-week period after entry into the growing-finishing unit.

  • Group three: growing pigs (n = 3810) received chlortetracycline hydrochloride (500 ppm), tylosin tartrate (100 ppm) and sulphadimidine sodium (1000 ppm) feed medication (SK 40 ad us. vet., Biokema, CH-1023 Crissier, Switzerland) during a 3-week period after entry into the growing-finishing unit.

  • Group four: growing pigs (n = 3809) were not treated.

Culling and mortality rates, reasons for culling and mortality, and average daily weight gain during the entire growing-finishing phase were evaluated. Porcine proliferative enteropathy (PPE) associated culling and mortality rates were lower (1.1%, 1.3% and 1.4% in groups 1-3, vs. 7.0% in the control group, P < 0.05).

Both vaccinated and feed-medicated pigs had lower non-PPE associated culling and mortality rates compared with the non-vaccinated pigs (2.1%, 2.3% and 2.5% vs. 5.9%, P > 0.05). Average daily weight gain was greater (P < 0.05) both in the LI vaccinated and feed-medicated groups of pigs compared with the untreated pigs (799 ± 49 g, 767 ± 48 g and 757 ± 39 g vs. 650 ± 92 g).

The present results indicate that both LI vaccination and feed medication at the beginning of the growing-finishing phase of the production, does not only prevent PPE, but might also result in more resistance and tolerance against other infectious diseases and multifactorial diseases.

Further Information

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Read more about: Boehringer Ingelheim's Enterisol® Ileitis

Boehringer Ingelheim Vetmedica, Inc.

November 2006